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Due to the nature of lozenge use, 100% of nicotine is extracted, but inevitably some of the extracted nicotine will be ingested and subject to first-pass metabolism by the liver 16

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Female mosquitoes have nerve cells called cpA neurons that have a receptor to detect carbon dioxide

Figure 11 Quit rates by socio-economic status (NZDep) (NZHS 2019/20 and 2020/21 with quintile 5 being the most deprived) Figure 12 shows that quit rates decrease greatly with age, and this age-related quitting gradient increased in 2020/1