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A recent large-scale clinical trial has confirmed that tirzepatide, a dual GIP and GLP-1RAs, resulted in a weight loss of up to 20.9% in adults with body fat mass of 30 or more after 72-week follow-up [22]

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If you have not seen meaningful weight loss after 3 months, review your diet, protein intake, and activity level with your provider

Free Radic Biol Med 173:125141 Bono S, Feligioni M, Corbo M (2021) Impaired antioxidant KEAP1-NRF2 system in amyotrophic lateral sclerosis: NRF2 activation as a potential therapeutic strategy